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INTERNATIONAL JOURNAL OF DIAGNOSTICS AND RESEARCH  
A Review On Shatkriyakala (Disease Progression) In Veiw Of Surgical Disease  
Management  
Dr.Dwivedi Amarprakash1, Dr.Batra Khushbu2  
1Professor, Department of Shalyatantra, School of Ayurveda, D.Y. Patil deemed to be University, Navi Mumbai,  
India.  
2 M.S. scholar, Department of Shalyatantra, School of Ayurveda, D.Y.Patil deemed to be University, Navi  
Mumbai, India.  
Corresponding Author: Dr. Batra Khushbu  
Article Info: Article Received on : 06/04/2026  
Article Reviewed on: 08/04/2026  
Article Published on : 15/04/2026  
Cite this article as: - Dwivedi, A., & Batra, K. (2026). A Review On Shatkriyakala (Disease Progression) In Veiw Of Surgical  
Disease Management. International Journal of Diagnostics And Research, 3(3), 75–82. https://doi.org/10.5281/zenodo.19597515  
Abstract  
Introduction- Shatkriyakala is a fundamental Ayurvedic concept describing the sequential stages of disease development  
arising from doshic imbalance. It enables early detection of pathological changes before clinical manifestation and supports  
preventive and stage-wise therapeutic intervention. With the increasing burden of lifestyle and chronic disorders,  
understanding this model is vital for effective and integrative disease management. Methods- A comprehensive literary  
review was conducted using classical Ayurvedic texts including Sushruta Samhita and Ashtanga Hridaya. Relevant  
references were critically analyzed to understand the concept, clinical relevance, and progressive nature of Shatkriyakala.  
Correlations with contemporary medical concepts were explored. Four clinical conditions— Hemorrhoids (Arsha), Fistula-  
in-Ano (Bhagandara), Appendicitis (Undukpuch shoth), and Cholecystitis (Pittashaya Shoth)—were reviewed for stage-  
wise clinical implications. Results- The six stages—Sanchaya, Prakopa, Prasara, Sthanasamsraya, Vyakti, and Bheda—  
demonstrated a systematic progression from subtle doshic imbalance to established disease and complications. Early stages  
were largely reversible through dietary regulation, lifestyle modification, and preventive therapy, whereas advanced stages  
required pharmacological intervention, Panchakarma, or surgical treatment. Stage-wise clinical application revealed that  
early Arsha responded to conservative therapy while advanced cases required hemorrhoidectomy; Bhagandara progressed  
from abscess to tract formation requiring drainage and definitive surgery; Appendicitis evolved from early inflammation to  
perforation necessitating emergency surgery; and Cholecystitis progressed from biliary colic to suppuration requiring  
cholecystectomy. Strong parallels were observed with modern concepts such as inflammation, localization, abscess  
formation, and chronic disease progression. Discussion and Conclusion- Shatkriyakala provides a structured and clinically  
applicable model for understanding disease pathogenesis. Its stage-wise approach facilitates early diagnosis, personalized  
treatment, and prevention of complications. Integration of this framework into clinical practice strengthens Ayurveda’s  
preventive philosophy and supports the development of integrative diagnostic and therapeutic strategies. Further research is  
needed to standardize its diagnostic application for broader clinical use.  
Keywords- Shatkriyakala, Six staged disease progression, Appendicitis, Haemmorrhoids, Arsha, Fistula-in-Ano,  
Bhagandara, Undukpuch shoth,Cholecystitis ,Pittashaya Shoth  
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disease expression and complications. The clinical  
significance of this concept lies in its ability to  
guide stage-wise management, enabling preventive,  
Introduction :  
Shatkriyakala is a fundamental Ayurvedic concept  
described by Acharya Sushruta that explains the six  
sequential stages of disease development from  
initial doshic imbalance to complete clinical  
manifestation and complications.[1] The term  
denotes both the progression of disease and the  
appropriate timing for therapeutic intervention,  
curative,  
and  
surgical  
interventions  
to  
be  
implemented at appropriate phases of disease  
evolution. [3]  
Materials and Methods :  
Literary Search - The references for this review  
were collected from classical Ayurvedic texts,  
mainly Sushruta Samhita and Ashtanga Hridaya.  
thereby  
pathogenesis (Samprapti).  
Sanchaya(~Stage of  
forming  
the  
basis  
[2]  
of  
Ayurvedic  
The six stages—  
Accumulation),  
1. In Sushruta Samhita, the term Kriyakala is  
mentioned in two contexts. In the concept of  
Chikitsa Chatushtaya, it refers to the  
Prakopa(~Stage of Aggravation), Prasara(~Stage  
of Spreading), Sthanasamsraya(~Stage of  
Localization) , Vyakti(~Stage of Manifestation),  
and Bheda(~Stage of Differentiation)—represent  
the evolution of pathology from subtle functional  
disturbance to structural disease and chronic  
complications.  
appropriate  
timing  
for  
therapeutic  
procedures such as Snehana, Shodhana, and  
Shastrakarma. In Sutrasthana Adhyaya 21,  
Acharya Sushruta describes Kriyakala as  
the six stages of disease development,  
In recent years, sedentary lifestyles, irregular  
known  
as  
Shatkriyakala  
(Vyadhi  
dietary  
habits,  
environmental  
pollution,  
and  
Kriyakala): Sanchaya, Prakopa, Prasara,  
Sthanasamsraya, Vyakti, and Bheda. These  
stages explain the sequential progression of  
disease and guide stage-wise therapeutic  
management. [4,5]  
psychological stress have led to a significant rise in  
chronic and lifestyle disorders. Failure to maintain  
internal homeostasis is the primary contributor to  
disease onset and progression, highlighting the  
need for early diagnosis and preventive strategies.  
2. In  
Ashtanga  
Sangraha  
(Sutrasthana,  
Unlike  
symptom-based  
approaches,  
Ayurveda  
Chapter 12), the concept of Ritu Kriyakala  
describes three phases —Chaya (Stage of  
accumulation of doshas), Kopa (Stage of  
emphasizes early detection by identifying Dosha  
imbalance before the development of overt disease.  
The pathogenesis of Shatkriyakala begins with the  
accumulation and aggravation of Doshas in their  
normal sites, followed by systemic spread through  
bodily channels and localization in susceptible  
tissues, resulting in Dosha-Dushya Sammurchhana  
(pathological combination).If timely intervention is  
not undertaken, this process progresses to full  
aggravation),  
Pacification  
and  
Prashama  
These  
(Auto  
stages  
of  
dosha).  
represent seasonal variations in Dosha  
status. Adoption of appropriate seasonal  
regimen (Ritucharya) helps in maintaining  
Dosha  
balance  
and  
physiological  
equilibrium. [6,7]  
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According to Acharya Sushruta, the six phases of  
dosha in the development of diseases are  
1) Sanchaya  
2. Prakopa (Stage of aggravation)  
The second stage, Prakopa, or aggravation, occurs  
when accumulated Doshas continue to increase due  
to the persistence of causative factors. The Doshas  
become provoked and begin to overflow within  
their respective sites, leading to more pronounced  
symptoms. In Vata Prakopa, the person may  
experience abdominal pain and hyperperistalsis; in  
Pitta Prakopa, sour eructations, excessive thirst,  
and burning sensations are observed; while in  
Kapha Prakopa, excessive salivation, nausea,  
heaviness, and anorexia occur. Vagbhata mentions  
that in this stage, the Doshas are ready to spread  
throughout the body.  
2) Prakopa  
3) Prasara  
4) Sthanasanshraya  
5) Vyakti  
6) Bheda  
1. Sanchaya( Stage of accumulation)  
The first stage, Sanchaya, marks the initial  
accumulation of Doshas in their specific sites due  
to various causative factors such as improper diet,  
lifestyle, and environmental influences. During this  
phase, Vata accumulates in Pakvashaya (large  
intestine), Pitta in Grahani (small intestine), and  
Kapha in Amashaya (stomach). The symptoms at  
this stage are mild and include stabdhapoorna-  
koshtata (abdominal stiffness and fullness) in Vata  
Sanchaya, pittavabhasata (yellowish discoloration)  
In modern terms, this stage indicates further  
derangement of homeostasis and may correlate with  
abnormal cell proliferation or increased DNA  
mutations caused by oxidative stress.  
3.Prasara (Stage of spreading)  
and  
mando  
ushmata  
(slight  
rise  
in  
body  
The third stage, Prasara, denotes the spreading of  
the aggravated Doshas from their original sites to  
other parts of the body through various srotas  
(channels). This condition arises when the doshas  
become aggravated and escape regulatory control,  
subsequently spreading beyond their primary sites.  
Vata Prasara produces atopa (bloating) and  
regurgitation, Pitta Prasara leads to fever and  
burning sensations, and Kapha Prasara manifests  
as anorexia,heaviness, indigestion, fatigue, and  
nausea. Classical texts compare this stage to milk  
overflowing from a heated vessel.  
temperature) in Pitta Sanchaya, and gaurava  
(heaviness), alasya (sluggishness), and nausea in  
Kapha Sanchaya. The individual may develop an  
aversion to factors that aggravate the Dosha and a  
liking for opposite qualities — Vata prefers warmth  
and unctuousness, Pitta craves coolness and  
sweetness, and Kapha tends toward fasting. As the  
symptoms are minimal and the imbalance is  
localized, this stage is important for preventive  
care, as timely intervention may completely reverse  
the pathology.  
From a contemporary perspective, this stage may  
correlate with early biochemical and oxidative  
stress–related changes at the cellular level.  
From modern perspective, this phase may be  
correlated with cellular migration or systemic  
inflammatory spread, where oxidative stress alters  
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cell adhesion and promotes diffusion throughout  
tissues.  
In modern terms, This stage is comparable to the  
acute or clinically apparent phase of disease  
manifestation  
in  
modern  
pathology,  
where  
4. Sthansanshraya (Stage of Localization)  
diagnosis is confirmed based on clear clinical signs  
and laboratory findings.  
The fourth stage, Sthanasamsraya, involves the  
localization of the aggravated Doshas in weak or  
susceptible tissues (Dushya). Due to structural  
defects or Srotodushti, the circulating Doshas settle  
in specific organs, forming a Dosha-Dushya  
Sammurchhana (pathological combination). This  
6. Bheda (Stage of differentiation)  
Finally, the sixth stage, Bheda, marks the  
differentiation or complication stage of disease. If  
left untreated, the illness progresses to chronicity,  
leading to complications, degeneration, or even  
fatal outcomes. At this stage, the disease can be  
identified precisely by its Doshaja type, such as  
Pittaja Atisara (diarrhea of Pitta origin). Prognosis  
is generally poor, and conditions may become  
irreversible or resistant to treatment. In modern  
terms, this phase corresponds to advanced or  
chronic disease states with structural and functional  
deterioration, comparable to complications or  
degenerative pathology. (Table-1)  
localized  
interaction  
produces  
Purvarupa  
(prodromal symptoms) such as pain, heaviness, or  
discomfort in the affected area, signaling the onset  
of a disease. The nature of the emerging disorder  
depends on the type of Dosha involved and the  
tissue affected. Timely use of Rasayana therapy  
and detoxifying measures at this stage can prevent  
further progression. In modern terms, This stage  
can be compared to the ―homing process‖ in  
modern medicine, where abnormal cells or agents  
localize  
to  
specific  
tissues,  
initiating early  
Stage  
Features  
Surgical Role  
Sanchaya  
(Accumulation)  
Prakopa  
(Aggravation)  
Prasara  
(Spread)  
Mild, vague, localized  
symptoms  
Symptoms more evident,  
inflammation begins  
Doshas/systemic spread,  
abscess formation  
Observation, Preventive care, No  
surgery  
Early medical/surgical intervention,  
prevent progression  
Minor surgical drainage, early  
operative planning  
pathological changes.  
5. Vyakti (Stage of Manifestation )  
The fifth stage, Vyakti, represents the full  
manifestation of the disease. When the Dosha-  
Dushya interaction intensifies,disease-specific signs  
and symptoms (Rupa) become evident, enabling  
diagnosis. This is the stage where the disease  
expresses itself clearly with all its distinctive  
features. For example, fever (Jwara), diarrhea  
(Atisara), or inflammation (Shopha) become  
evident. The symptoms can be divided into  
Samanya Lakshanas (common symptoms due to  
increased Dosha) and Pratyatma Lakshanas  
(specific symptoms unique to that disease).  
Sthanasamshraya  
(Localization)  
Vyakta  
(Manifestation)  
Bheda  
Local pathology well-defined Plan definitive surgery  
Disease fully expressed with  
Targeted, condition-specific surgery  
signs & symptoms  
Complicated/advanced  
disease  
Radical or staged surgery, recurrence  
prevention  
(Complication/Chronic)  
Table 1: Showing six stages of shatkriyakala(  
Disease progression) [8]  
Clinical application of Shatkriyakala (Disease  
progression) in common surgical disease. :  
Shatkriyakala highlights the importance of early  
diagnosis and timely intervention, guiding the use  
of preventive, medical, and surgical management at  
appropriate stages. Thus, it serves as a practical  
framework for stage-wise treatment planning and  
the prevention of complications. The following  
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Haemorrhoids (Arsha) [12,13]  
Disease progression  
:
Clinical Features  
tables provide an overview of the application of  
Shatkriyakala in four common surgical diseases,  
correlating each stage with disease progression,  
clinical features, and stage-wise management. This  
demonstrates the transition from early reversible  
pathology to advanced complications, along with  
Stage  
(Shatkriyakala)  
Management  
Predisposing factors such Heaviness, constipation, Nidana Parivarjana (avoid  
as chronic constipation, mild discomfort; early causative factors), high-fiber  
prolonged straining,  
dosha chaya without  
diet, hydration, bowel  
regulation, lifestyle  
correction.  
sedentary lifestyle leading clear pathology.  
to venous congestion in  
hemorrhoidal plexus  
Sanchaya  
(Kapha-Vata imbalance  
due to Viruddhadhyasan,  
Vega Dharana, Ati Asana,  
Striprasanga).  
corresponding treatment preferences.  
[9,10,11]  
Increased venous pressure Straining during Shamana Chikitsa, bowel  
with persistent congestion defecation, discomfort, regulation, stool softeners,  
Appendicitis (Undukpuch shoth)  
:
and early vascular  
dilatation (Vata-Pitta  
aggravation). Dosha  
prakopa individually or in  
combination.  
occasional bleeding;  
aggravated bowel  
symptoms.  
sitz bath; early medical  
intervention.  
Stage  
(Shatkriyakala)  
Prakopa  
Prasara  
Disease progression  
Clinical Features  
Management  
Sluggish gut motility,  
luminal stasis with mucus Vague abdominal  
inspissation and lymphoid discomfort,mild  
Dietary modification,  
Langhan-Deepana-Pachana-  
Anuloman,Nidanparivarjan.  
Sanchaya  
hyperplasia ( Kapha  
accumulation)  
anorexia  
Progressive dilatation of  
hemorrhoidal veins with  
early pile formation and  
mucosal irritation; doshas doshic spread.  
spread via Dhamanis.  
Itching, mild bleeding Conservative management—  
per rectum, mucus  
discharge; systemic  
dietary measures, laxatives,  
topical therapy; Shodhana  
(purificatory measures) if  
required.  
Low fiber diet, refined  
carbohydrate intake, and  
irregular bowel habits  
contribute to luminal  
obstruction (fecolith,  
stricture, tumor, or  
parasites), resulting in  
mucosal irritation and early  
inflammation (Vata–Pitta  
aggravation).‖  
Mild abdominal pain,  
bowel  
irregularity,localized  
mucosal edema and  
congestion  
Early intervention-Shamana  
chikitsa, diet and lifestyle  
correction  
Prakopa  
Localization in Gudavali Poorvarupa: anorexia, Dosha–Dushya targeted  
(ano-rectal region) with emaciation, anemia, pain treatment; medical therapy,  
formation of hemorrhoidal in anal region; later pain, local applications, and  
masses due to tissue  
weakness and vascular  
engorgement (correlates  
with Grade I–II  
bleeding, intermittent  
prolapse.  
procedures like sclerotherapy.  
Sthanasamshraya  
Obstruction leads to  
bacterial proliferation and  
release of inflammatory  
mediators, causing  
increased intraluminal  
pressure, edema, and  
mucosal ulceration  
facilitating bacterial  
translocation into the  
submucosa and peri-  
appendiceal tissues, thereby  
initiating an early  
hemorrhoids).  
Antimicrobial and anti-  
Increasing pain, nausea, inflammatory drugs by  
Fully manifested  
hemorrhoids with  
Prolapse, bleeding,  
discomfort, mucus  
discharge; distinct types hemorrhoidectomy depending  
of Arsha with classical on grade; Vyadhi-specific  
Kshara karma, rubber band  
ligation, or  
Prasara  
low-grade fever  
parental route,IV Fluids,  
vitals monitoring.  
significant prolapse and  
vascular changes (Grade  
II–III/IV). Clear disease  
expression after Dosha–  
Dushya Sammurchana.  
Vyakti  
Bheda  
features.  
chikitsa.  
inflammatory cascade.  
Localized appendiceal  
inflammation-mucosal  
Vague abdominal  
Sthanasamshraya edema, compromised blood discomfort,tenderness, Antibiotics, IV Fluids.  
Complicated  
Severe pain, non-  
Surgical hemorrhoidectomy,  
flow, local irritation ( Ama mild fever,malaise  
involvement)  
Severe Right lower  
hemorrhoids—thrombosis, reducible mass, profuse excision of thrombosed piles,  
strangulation, ulceration, bleeding; complications emergency care;  
irreducible prolapse;  
chronic progression and  
differentiation.  
quadrant pain,  
McBurney’s point tre  
like Gulma, Plihodara Vyadhipratyanika chikitsa.  
etc.  
Established acute  
appendicitis with clear  
clinical manifestation  
enderness, vomiting,  
nausea with clinical  
signs such as-muscle  
guarding,rovsings  
Appendectomy(lap/open)  
with antibiotic coverage.  
Vyakti  
Bheda  
sign,psos sign,obturator  
sign,leukocytosis  
Fistula-in-ano (Bhagandara) [13,14,15]  
:
Complicated  
appendicitis—  
perforation,gangrene, per-  
appendiceal abscess,  
peritonitis,  
Heamodynamically  
unstable, Severe  
systemic detoriating  
Emergency surgical  
intervention-Laparotomy  
(emergency open  
Stage  
(Shatkriyakala)  
Disease progression  
Clinical Features  
Management  
signs and septic shock, appendectomy with peritoneal  
guarding, rigidity lavage)  
sepsis,mucocoele  
Predisposing factors such Mild itching, perianal  
as poor hygiene, chronic  
constipation, and  
cryptoglandular stasis  
leading to micro-  
inflammation in anal  
glands (Kapha-Pitta  
imbalance).  
Hygiene maintenance, dietary  
correction (high-fiber diet),  
bowel regulation, Nidan  
Parivarjan such as avoiding  
long term sitting on hard  
surfaces-sqatting posture.  
discomfort.  
Cholecystitis (Pittashaya Shoth) [9,10,11]  
Disease Progression (Modern  
Correlation)  
Sanchaya  
Stage (Shatkriyakala)  
Clinical Features  
Management  
Biliary stasis with thickened  
bile (sludge formation) due to Dyspepsia, heaviness  
Low-fat diet, Deepana-  
Pachana, Nidana Parivarjan,  
Obstruction and infection Pain, mild swelling,  
of anal glands with burning sensation,  
bacterial proliferation discomfort during  
causing early inflammation defecation.  
(Vata-Pitta aggravation).  
Pitta-kapha Shamana  
Chikitsa, sitz bath, stool  
softners, medicated oil basti  
chikitsa, antibiotics (if  
required).  
Sanchaya  
impaired gallbladder motility after fatty meals, mild Antacids, lifestyle  
abdominal discomfort. modification (avoid heavy  
meals)  
and bile supersaturation  
(Kapha-Pitta accumulation).  
Prakopa  
Prasara  
Aggravation leading to  
gallstone formation and/or  
intermittent cystic duct  
obstruction causing mucosal  
irritation (Pitta-Kapha  
aggravation).  
Fat intolerance,  
Spread of infection into  
surrounding tissues  
(intersphincteric space)  
Severe throbbing pain, Antibiotics, anti-inflammatory  
swelling, redness and  
discomfort at perianal  
bloating, mild right  
hypochondriac  
discomfort (biliary  
colic).  
Pitta-Kapha shamana, dietary  
regulation, analgesics(except  
opiods)observation.  
medications, local  
fomentation, incision and  
drainage (I&D).  
Prakopa  
Prasara  
leading to anorectal abscess region, fever.  
formation.  
Persistent obstruction leads to  
inflammatory changes in  
gallbladder wall with edema,  
chemical inflammation, and  
early infection.  
Medical management—  
analgesics(opiods are  
contraindicated), anti-  
inflammatory drugs,  
antibiotics, monitoring.  
Localization of abscess  
(Guda Vidradhi) with pus erythema, localized  
collection and tissue pain, possible  
Tender swelling,  
Incision and drainage, wound  
care,kshar-application for  
early sinus tract,  
Increasing right upper  
quadrant pain, nausea,  
vomiting, low-grade  
fever.  
Sthanasamshraya  
damage; early sinus tract discharge,difficulty in antibiotics,regular bowel  
formation may begin.  
sitting and defeacation. habits, monitoring for tract  
formation.  
Localization of inflammation  
in gallbladder—acute  
Sthanasamshraya cholecystitis with cystic duct  
obstruction, gallbladder  
distension, and wall thickening.  
Right upper quadrant  
Formation of a well-  
defined fistulous tract  
connecting anal canal to  
perianal skin (post-abscess in perianal  
stage).  
Persistent pus discharge Ksharasutra therapy,  
from external opening, fistulotomy/fistulectomy, or  
recurrent pain,induration seton placement.  
pain, positive Murphy’s Hospitalization, IV fluids,  
sign, Boa’s sign, fever, antibiotics, supportive care.  
vomiting.  
Vyakti  
region,swelling,itching.  
Established acute cholecystitis Severe RUQ pain, fever,  
Complex fistula with Chronic discharge,  
multiple branching tracts, multiple openings,  
Advanced surgical  
management (fistulectomy,  
advancement flap),  
Ksharasutra in complex  
cases, long-term follow-up.  
with marked inflammation,  
leukocytosis, guarding, Definitive management—  
positive imaging laparoscopic cholecystectomy  
confirmation (USG showing findings, jaundice, clay with antibiotics,ERCP,MRCP.  
Vyakti  
Bheda  
leukocytosis, and imaging  
recurrence, fibrosis, and  
possible sphincter  
induration, recurrent  
abscess,  
wall thickening, stones).  
colored stool  
involvement leading to  
incontinence risk. Chronic  
variants described by  
acharya sushruta-  
shatponak, paristravi,  
upnaha,unmargi,etc  
Bheda  
Complicated cholecystitis—  
gangrene, perforation,  
empyema of gallbladder,  
peritonitis,pancreatitis, sepsis.  
Severe systemic illness, Emergency surgical  
high fever, rigidity,  
signs of sepsis.  
intervention, drainage,  
intensive care management.  
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cholecystitis, haemorrhoids, and fistula-in-ano—by  
Discussion :  
correlating each stage with disease progression,  
The concept of Shatkriyakala offers a stage-wise  
clinical features, and management. The tabulated  
representation clearly highlights that early stages  
such as Sanchaya and Prakopa correspond to  
subclinical or mild pathological changes, which are  
largely reversible with dietary regulation, lifestyle  
modification, and Shamana therapy.As the disease  
progresses to Prasara and Sthanasamshraya,  
framework for understanding disease progression,  
closely  
aligning  
such  
with  
modern  
pathological  
infection,  
principles  
as inflammation,  
localization, and complication. The sequential  
transition from Dosha accumulation to systemic  
spread and eventual localization shows similarities  
with the evolution from functional disturbance to  
structural pathology recognized in contemporary  
science. The clinical correlations drawn in  
pathological  
inflammation, localization, and abscess formation  
become evident, requiring active medical  
processes  
such  
as  
spread  
of  
conditions  
like  
haemorrhoids,  
fistula-in-ano,  
management and minor surgical interventions. In  
appendicitis, and cholecystitis demonstrate that  
early stages are largely reversible with preventive  
and conservative management, while advanced  
advanced stages like Vyakti and Bheda, where  
structural  
definitive  
damage  
surgical  
and  
complications  
such  
occur,  
as  
procedures  
stages  
needs  
pharmacological  
or  
surgical  
appendectomy  
,
cholecystectomy,  
intervention. This highlights the practical relevance  
of Shatkriyakala in early diagnosis, timely  
intervention, and prevention of disease progression.  
Integrating Ayurvedic insights with modern surgical  
understanding enhances clinical decision-making  
and supports a more holistic, stage-based approach  
hemorrhoidectomy, and fistula surgery become  
necessary. Modern surgical literature also supports  
this progressive pattern, where conditions like  
appendicitis begin with luminal obstruction and  
inflammation and may progress to perforation and  
peritonitis if untreated. Similarly, cholecystitis  
to  
disease  
management.  
The  
concept  
of  
progresses  
from  
gallstone  
and  
obstruction  
to  
Shatkriyakala provides a comprehensive and  
dynamic framework for understanding disease  
progression, closely paralleling the natural history  
of disease described in modern medicine. The  
sequential stages—from Dosha accumulation to  
complication—demonstrate a logical transition  
from functional disturbance to structural pathology,  
comparable to processes such as inflammation,  
inflammation,  
infection,  
complications  
requiring surgical removal of the gallbladder. This  
stage-wise correlation emphasizes that  
Shatkriyakala is not merely a theoretical concept  
but a clinically applicable model for decision-  
making, enabling timely selection of preventive,  
medical, or surgical treatment. It reinforces the  
Ayurvedic principle of Samprapti Vighatana,  
aiming to arrest disease progression before  
infection,  
abscess  
formation,  
and  
chronic  
degeneration.In the present review, its clinical  
applicability has been demonstrated through four  
irreversible  
damage  
occurs.Furthermore,  
integrating Shatkriyakala with modern surgical  
common  
surgical  
conditions—appendicitis,  
Copyright @ : - Dr.Batra Khushbu Inter. J.Digno. and Research IJDRMSID0111 |ISSN :2584-2757  
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Ayu Int Med Sci. 2024;9(4):155-158.  
understanding enhances the scope of integrative  
medicine, providing a holistic approach that  
combines early diagnosis, individualized treatment,  
and appropriate surgical intervention. Thus, this  
concept holds significant potential in improving  
clinical outcomes and reducing complications when  
applied systematically in practice.  
Available  
From  
4. Susrutha Samhita by Kaviraj Ambikadutt  
Shastri. Chapter 34. Chaukhambha Sanskrit  
Prakashan Varanasi.  
Conclusion :  
5. Susrutha Samhita by Kaviraj Ambikadutt  
Shatkriyakala serves as a valuable bridge between  
classical Ayurvedic principles and modern clinical  
practice by providing a systematic approach to  
disease evolution and management. Its emphasis on  
Shastri.  
Chapter  
21  
page  
no  
90.  
Chaukhambha Sanskrit Prakashan Varanasi.  
6. Astang Sangraha by Ravidutt tripathi, Sutra  
early  
detection  
and  
stage-wise  
intervention  
Sthana  
12thch,  
by  
Choukhambha  
reinforces the importance of preventive healthcare  
while also guiding appropriate medical and surgical  
treatment in advanced stages. The correlations  
established in this review underline its applicability  
across a spectrum of diseases, demonstrating its  
relevance in integrative medicine. Adapting this in  
clinical practice can improve patient outcomes by  
Publication Varanasi.  
7. Vagbhat, Ashtanga Hridayam, Shastri HS,  
Paradkar (editor), Choukhambha Sanskrit  
Sansthan Varanasi. Sutrasthana 3/18 page  
no. 42.  
enabling  
timely  
and  
targeted  
management;  
8. Geetu Rathour. Concept and significance of  
Shatkriyakala. J Ayurveda Integr Med Sci  
[Internet]. 2024 Jun. 15 [cited 2026 Apr.  
however, further research and standardization are  
essential to validate and expand its use in evidence-  
based practice  
4];9(4):155-8.  
Available  
from:  
References :  
1. Susrutha Samhita by Kaviraj Ambikadutt  
Shastri. Chapter 21. Chaukhambha Sanskrit  
Prakashan Varanasi.  
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Practice of Surgery. 27th ed.  
2. Chauhan A, Semwal DK, Mishra SP,  
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12. Kumar, D. A. ., Dasar, D. D. ., & Sharma,  
D. P. . (2023). A Conceptual Study of  
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Declaration :  
Conflict of Interest : None  
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